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The efficacy shown with trastuzumab emtansine (T-DM1) further validated the ADC approach as both efficacious and tolerable.
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To assess whether concurrent blood flow restriction (BFR) during low-load resistance training is an efficacious and tolerable means of improving quadriceps strength and volume in women with risk factors for symptomatic knee osteoarthritis (OA).
Azacitidine was efficacious and tolerable in these older patients.
In conclusion, dexrazoxane proved highly efficacious and tolerable in the management of accidental anthracycline extravasation.
A recent study showed that KBr was less efficacious and tolerable than PB as first-line drug [ 10].
The all-oral HCV therapy, highly efficacious and tolerable in the majority of patients, will become available in 2014.
In the adjuvant setting, the Eastern Cooperative Oncology Group (ECOG) 1199 trial further supported this schedule of paclitaxel as efficacious and tolerable [ 20].
These groups were followed until the interim analysis, at which point isotretinoin 0.3 mg/kg stood out as the most efficacious and tolerable dosage.
A number of clinical studies with the EGFR-antibody cetuximab have shown that its application is efficacious and tolerable, with the most common toxicity being acneiform rash.
regimen simulated for ESRD resulted in a mean exenatide concentration profile within the therapeutically efficacious and tolerable range (<350 pg ml−1); however, this has not been clinically tested.
The plethora of emerging small-molecule ADAMTS aggrecanase inhibitors gives hope that some will be efficacious and tolerable and that those that are specific to ADAMTS5 could be developed as novel therapeutics for arthritis patients in the near future.
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