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If further animal trials confirm that L-783,281 or chemical variants resembling it are both effective in lowering blood sugar concentrations and safe, Merck says clinical trials might be feasible.
74 78 79 Step-up therapy with allopurinol (300 600 mg) or benzbromarone (100 200 mg) are both effective in lowering SUA levels.
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analysis showed that both substituents are effective in lowering the crystal melting and low-temperature crystal-crystal transitions with respect to the diethylsiloxane homopolymer, and ultimately lead to non-crystalline copolymers.
D.s.c. and dynamic mechanical analysis show that both substituents are effective in lowering the crystal melting and low-temperature crystal-crystal transitions with respect to the diethylsiloxane homopolymer, and ultimately lead to non-crystalline copolymers.
19 Similar to previous studies, our results show that both techniques are effective in lowering the IOP, and at the end of the follow-up period, there was no significant difference between the two groups, although the mean IOP of the two-site group was lower (P=0.058).
30, 31 The largest trial, however, did not confirm this over a large dosing range from 2.3 4.5 g. 32 The fourth trial compared the efficacy of once-daily dosing with 3.8 g versus twice-daily dosing with 1.9 g and found both regimens equally effective in lowering LDL-C.
In addition, the perforated flat plate absorber was effective and the UTC is effective in lowering both life cycle cost and energy used.
Our study shows that 6-month of dynamic exercise training was effective in lowering both systolic and diastolic blood pressure in a similar manner.
The BM treatment simultaneously improved the digestibility of both glucan and xylan, and was effective in lowering the enzyme loading compared with the HCW treatment.
Prior preclinical studies have shown that both active and passive immunotherapies were effective in lowering plaques in transgenic APP mice when performed as a preventative treatment; however, when performed as a therapeutic approach in aged transgenic mice, they lacked any effect on plaque levels [ 15, 50].
In several clinical trials, drugs with anti-inflammatory effects have shown to be effective in lowering AF incidence after CABG and/or valve surgery.
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