Sentence examples for both during normal development from inspiring English sources

These observations raise the intriguing possibility that FGF signaling, acting via downstream targets such as Lin28 and FoxD3, might have a general role in regulating pluripotency or the competence of embryonic cells to respond to signals which direct differentiation both during normal development and in culture.

Chromosomal DNA replication is the major driving force for cell proliferation both during normal development and in cancer.

Autophagy is implicated in homeostasis and cell-size regulation in multiple organs both during normal development and under stress conditions.

Integrin-matrix interactions are essential for building blood vessels both during normal development and in tumors, both primaries and metastases.

Proliferation of smooth muscle cells is an important component of pulmonary arterial morphogenesis, both during normal development and pathologic remodeling.

"We look at how things happen in the body, both during normal development and pathological function, and reproduce these conditions using engineering principles," says Vunjak-Novakovic.

Previous studies have indicated that RET can receive both cis and trans signals using cultured cells, but it was not clear whether both types of signal occur during normal development and contribute to the same biological processes.

Both dehydrins and LEAs have been shown to be expressed during normal development and to be water stress responsive in conifers [ 18, 27, 28].

The developing vasculature guaranties the needed supply of nutrients and, during normal development, serves as a template for the forming bone.

Both morphogenetic movements and cell division patterns are well characterized and are tightly regulated during normal development.

Both BMPs and their cognate receptors have been shown to be expressed by OLs during normal development (Cheng et al., 2007; See and Grinspan, 2009).