Furthermore, the total dinucleotide-based stiffness parameter ktotal (see Methods for definition) unveiled that LRs (in both naked and nucleosomal DNA) are located in regions with large variations in flexibility, where an extremely flexible site is surrounded by stiff motifs.
Specifically, this increase is centered in exon 4, where the majority of the residues contacting DNA are located.
As shown in Figure 11B, the binding sites for ATP and DNA are located quite far apart in the protein structure.
Although RNA molecules are synthesized in the cell nucleus, where the DNA is located, most of them are transported to the cytoplasm before they carry out their functions.
In the control sets (0 min incubation), most of the DNA is located in the head of the comet while cells subjected to longer treatment show increasing DNA damage and longer comet tails.
A two phase system is discussed, in which the DNA is located in buffered solution whereas the hydrophobic porphyrins, responsible for the charge separation reaction, are located in the lipid bilayer of liposomes or supported lipid bilayers.
The fluorescent anti-PARP-1 staining outlines the perimeter of the S. solfataricus cells (Fig. 1a, bottom left; green), as does the membrane staining (Fig. 1a, top, right; red), while the DAPI-stained DNA is located in the cell centre (Fig. 1a, top middle; blue).
In eukaryotes, genomic DNA is located in the cell nucleus, along with small amounts in mitochondria and chloroplasts.
In eukaryotes, DNA is located in the cell nucleus, as well as small amounts in mitochondria and chloroplasts.
Being a transcription factor, a protein that binds to specific DNA sites and thereby regulates the activity of specific genes, Tbr1 is localized in the nucleus where the cell's DNA is located.
