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This research addresses the need to deal with complex dependencies between systems, in both developmental and functional relationships.
Neuroanatomy is the foundation of both developmental and functional studies of the brain.
Both developmental and functional constraints limit the range of observed changes in morphology, and these limits may require more complex models than were implemented here.
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Early-onset depressive disorders can have severe consequences both from developmental and functional aspects.
The recent identification of a central role for miR-124 in neurogenesis and synaptic plasticity integrates this microRNA into the full repertoire of neuronal events, particularly at both the developmental and functional aspects.
Our results unravel the integration of different aspects of the adult phenotype into developmental and functional units which both reflect and impact evolutionary change.
To assess the utility of a telephone-based interview system in providing ongoing monitoring of the developmental and functional status of children with both positive newborn screens for Krabbe disease and low galactocerebrosidase activity on confirmatory testing, and to determine whether this approach provides improved compliance with follow-up compared with formal neuropsychological testing.
Overall, our data suggests that aging affects LCs development and function, and that age-regulated miRNAs may contribute to the LC developmental and functional changes in aging.
Depressive illness beginning early in life can have serious developmental and functional consequences.
To describe developmental and functional outcomes of children with congenital heart defects (CHDs) at school entry after open heart surgery.
While the brain is replete with miRNAs, their particular role(s) in the developmental and functional programs of neurons is just emerging.
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