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In mature trabecular bone, both density and trabecular orientation are adapted to external mechanical loads.
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When combining the areal Bone mineral Density and Trabecular Bone Score, the Trabecular Bone Score remains a predictor of fracture but not the areal Bone Mineral Density.
The trabecular scaffolds matched bone samples in porosity; however, achieving physiologic connectivity density and trabecular separation will require further refining of scaffold processing.
Micro CT was used to compare porosity, connectivity density, and trabecular separation of each scaffold type to a canine trabecular bone sample.
Increased trabecular thickness and separation and reduced cancellous bone volume fraction, connectivity density, and trabecular number were detected in proximal tibia and lumbar vertebra 14 days following γ-irradiation with 6 Gy.
This suggests that in vivo μCT may be used to evaluate change in mineralized bone density and trabecular architecture over time, which may be caused by disease or therapy, for example, in animal models.
At the tibia, Hispanic women had lower trabecular volumetric bone density and trabecular number, and higher trabecular separation.
Whole bone stiffness, trabecular bone density and trabecular plate parameters were also lower in post- versus premenopausal women.
The 5th lumbar vertebrae were used for bone mineral density and trabecular bone structure measures.
Daily injections of 50 mg/kg/day of melatonin significantly increased bone mineral density and trabecular structure in mice[ 15].
Abudusaimi et al., Xie et al. and Aimaiti et al. used micro CT scan to evaluate bone volume, bone mineral density and trabecular volume [ 10, 32, 34].
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