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The data presented here are complementary to those obtained using BACFA analysis in that both data sets suggest a scenario where H37Rv is better equipped to adapt to intracellular environments.
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Despite this similarity in the pattern of demographic characteristics between our sample and the national data, the proportion of GPs attending RCF in our sample was higher than in the national data-set, suggesting a volunteer bias.
Both data sets suggested that the combination reversed the down-regulation of the expression of genes related to innate immune responses observed with CPT-11 treatment.
The corresponding regression for genes outside of the aberrations is nearly horizontal for both data sets, suggesting that the observed correlations are not a product of a bias in the expression data.
The majority of the cDNAs that were significantly differentially expressed were assigned to the same group in both data sets suggesting a minimal impact of the false positive and negative errors in this study.
The fact that this is observed in both data sets suggests that it may not be a chance finding (although chance cannot be entirely discounted), the explanation for which is not clear to us.
The recovery of an eocyte tree, rather than the three domains tree, from both data sets suggests that this result is robust to the choice of genes, alignment methods, or masking protocols.
In general, a few highly connected 'hub' genes, some with known subtype-specific involvement appear to hold together components of these networks for both data sets, suggesting their central roles in these subtypes.
Visual inspection of the quartile ranges in both data sets suggested that the highest pain intensity reports of the experimental group (50th percentile and greater) overlapped with the lowest pain reports (50th percentile or lower) of the patients seeking intervention for their back pain - 16 to 68 mm, and 0 to 50 mm respectively.
Thus, both these data sets suggest that D is higher in neuronal transcriptomes than in endothelial transcriptomes among primates.
Thus, both spatial and spectral data sets suggest that live tree biomass C stocks can continue to accumulate in Japanese cedar stands over 90 years old.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com