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Both cutoff points are determined to provide a specificity level of 75% for the CA125 plus HE4 assay combination.
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We therefore propose a parametric version in which the estimates of the predictive performance and cutoff points are both essentially unbiased.
The cutoff points are jointly significant at 1% level.
To save space, the estimated cutoff points are not reported.
The bandwidth and cutoff points are defined to derive a more stable frequency point, namely center frequency fc.
Such cutoff points are recommended for future trials.
Similarly for plant metabolites, the following cutoff points are proposed.
As can be seen in Figure 1, two cutoff points are expected to be found.
In Table 2, the diagnostic properties of different A1C cutoff points are described.
These cutoff points are used in the criteria of the metabolic syndrome by the National Cholesterol Education Program Adult Treatment Panel III (10).
With regard to ROMA, different cutoff points are used in pre-menopausal and post-menopausal patients.
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