Sentence examples for both core and accessory from inspiring English sources
Known virulence determinants and immunogenic proteins are present in both core and accessory genome, with 23 (1.7%) in the former and 15 (2.4%) in the latter (Table S2).
Both core and accessory orthologs occasionally appear in more than one COG class.
To accomplish this, we developed a new software algorithm for identification of both core and accessory genomes from bacterial genome sequences.
Future work should seek to understand the evolutionary dynamics of both core and accessory genes as a function of the networks in which they participate.
The results of this study, and others, support the notion that the products of both core and accessory genes participate in complex networks that comprise the molecular basis of virulence.
Despite the strong evidence for appreciable rates of recombination in these P. aeruginosa genomes, our phylogenetic analyses consistently identified the same set of clades (Clades A E) as distinct in both core and accessory genomes.
In addition, genes responsible for antimicrobial resistance and non-ribosomal peptide/polyketide synthesis are present in both the core and accessory genome of each strain.
Proteins of both the core and accessory data sets with homologs in M. mitochondrii (n = 138) were highlighted, and regions of synteny between the M. mitochondrii genome and CDS from several T. adhaerens scaffolds were superimposed on the plot.
To compare chromatin structure between core and accessory chromosomes both in centromeric regions and near telomeres, we performed ChIP-seq with antibodies against one mark for euchromatin, H3K4me2, one mark for obligate heterochromatin, H3K9me3, and one mark for facultative heterochromatin, H3K27me3 (Figs. 5, 6, Additional file 2: Table S1, Additional file 3: Figure S2).
Thus, genomes with core and accessory components seem a common evolutionary strategy for both, temperate and virulent phages.
