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Here, we review the state of the art on 2D piezoelectricity, with reference to both computational predictions and experimental characterization.

The currently accepted phase diagram for the Ag-Pt system is questionable because of its disagreement with earlier experiments and because of its claim for a lone ordered structure at 53%-Pt which was not characterized and which contradicts both computational predictions and analogy to the isoelectronic system Cu-Pt.

However, we do not include these for HINT as they integrate both computational predictions and experimentally determined interactions.

However, GO annotation based on both computational predictions and extended manual curation has so far only been available for one of its species, namely A. nidulans.

This is consistent with the statistic that the GOA database (including both computational predictions and literature-based annotations) did not include any annotations for ∼31% of the entries in UniProtKB in 2005 (7).

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A. nidulans is the only Aspergillus species for which comprehensive GO annotation based on both computational prediction and extended manual curation of gene-specific literature is available [ 9].

As shown in Figure 4C, the R43P variant displayed a lower propensity for helix formation with a lower cooperativity, consistent with both decreased helix nucleation and propagation, as also evident from both the computational predictions and the NMR data.

miRNA targeting information derive from both experimental data and computational predictions, and protein drug interactions are annotated by the Pharmacogenomics Knowledge base (PharmGKB).

There is a number of both computational and molecular biological difficulties that make computational predictions and cloning of the genetic variants of OPRM1 highly challenging.

There is good agreement between computational predictions and experimental results.

SR selected the subproteomic studies, carried out the computational predictions and performed their analyses.

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