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The release of both compounds has been shown to depend on the temperature and pH value of the environment.
Since higher affinity of dimeric compounds is often caused by reduced dissociation rates, the cell surface retention of both compounds has been studied in a cell surface retention experiment.
The strong antagonistic effect of both compounds has been demonstrated for cellular metabolism and total protein contents in the hepatocytes.
This is similar to the situation in Arabidopsis thaliana, in which genes regulated by 5-AzaC and TSA do not overlap, although a synergistic effect of treatment with both compounds has been observed [ 33].
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Complete crystal data parameters for both compounds have been provided in Table 1.
Both compounds have been characterized by single X-ray crystallography, IR spectroscopy, TGA and elemental analysis.
The structures of both compounds have been determined by single-crystal X-ray crystallography.
Both compounds have been synthesized in high yields and characterized by spectroscopic as well single crystal diffraction studies.
The chemical shift calculations of both compounds have been performed by using the fully optimized geometries, adopting the GIAO method at the same level of theory and referred by using the internal reference standard i.e. trimethylsilane.
Reaction kinetics for the catalytic oxidation of H2S and PH3 over the mixed catalyst has also been studied on differential reactor, and kinetic model for both compounds have been formulated, which are subsequently implemented in the modeling of the pilot-plant fixed-bed reactor.
Both compounds have been reported to modulate voltage-gated sodium channel activity.
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