Sentence examples for both classes of mutations from inspiring English sources

That is, both classes of mutations are subject to interference, not genetic drift, as a dominant stochastic force.

In the MK test, which also considers polymorphic data, the two classes of mutations are assumed to be evolutionarily equivalent: patterns of polymorphism and divergence should therefore be the same for both classes of mutations.

Nevertheless, the mean sojourn times of newly arising neutral and deleterious mutations are quite similar (roughly 20% longer for neutral than for deleterious mutations) because a large fraction of both classes of mutations are lost soon after arising (fig. 4, middle panel).

Both of these classes of mutations prevent the transcriptional activation of p53 target genes in a dominant-negative fashion (Vousden et al., 2002).

Among the six strains, only one had two classes of mutations (both NRTI and NNRTI) (Table 2).

Here, we have extended the Beerenwinkel model to describe multiple classes of mutations; both deleterious and advantageous mutations, and other mutation classes that do not directly impact on a cell's fitness.

Studies of mutated loxP sites have revealed that two classes of mutations can promote Cre-mediated insertion or replacement.

Several classes of mutations that affect the pattern of the egg or the body pattern of the embryo were identified.

This gives it up to 2x lower error rates than current tools and lets it match classes of mutations, such as longer indels, that these tools miss.

The result is an algorithm that scales well for reads from one hundred to thousands of bases long and provides a rich error model that can match classes of mutations (e.g., longer indels) that today's fast aligners ignore.

In addition, we paint a broad picture of the genetic landscape of the species by functionally annotating different classes of mutations with a well-established prediction tool (PolyPhen-2).