Sentence examples for both cellular models and from inspiring English sources
This hypothesis is based on information obtained using both cellular models and model organisms.
The experimental outcomes showed that KRIT1 loss of function is associated with the upregulation of c-Jun in both cellular models and human CCM tissue samples.
The findings of the present study, emerging from both cellular models and computer-assisted modeling of TDP-43, suggest that the first 10 amino acid residues of TDP-43 are essential for proper monomer folding, homodimer formation and splicing activity.
Here, we show that KRIT1 loss of function leads to enhanced expression and phosphorylation of the redox-sensitive transcription factor c-Jun, as well as induction of its downstream target COX-2, in both cellular models and human CCM tissues.
We first tested this transgene in cell culture models, and found that the mRNA levels of hSOD1 T116X were about half of that of hwtSOD1 in both cellular models (Fig. 2A and B).
The fidelity of cell culture simulations of traumatic brain injury (TBI) that yield tolerance and mechanistic information relies on both the cellular models and mechanical insult parameters.
Previous results from our laboratory indicated a positive correlation between high mRNA expression levels of MMPs and their inhibitors with breast cancer progression, both in cellular models and in tumor tissue samples, with all five human breast cancer cell lines displaying different invasive and metastatic potential when maintained in culture for 3 or 5 days [ 12].
This review addresses information available both from in-vitro cellular models and in-vivo animal models that have been designed to investigate mitochondrial DNA segregation in somatic and in germ cells at different stages of development.
For both cellular models the grade of differentiation was determined by Oil red O staining for fat vacuoles (Fig. S7).
As expected, irradiation resulted in a cell cycle arrest in both cellular models.
After prolonged treatment with these pharmacological agents, a differentiated phenotype was observed in both cellular models.
