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In contradistinction, CD146 was detectable in tissues on both cellular components of tumor vessel wall: CD31(bright)CD45- endothelial cells and alpha-SMA+ pericytes.
Both cellular components of this system are thus autologous to a single donor.
The central feature of the system is that both cellular components of the system (i.e. iPS cells and their supporting feeder cells) originate from a single cell source.
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The majority of approved recombinant monoclonal antibody therapies are of the human IgG1 subclass, which can engage both humoral and cellular components of the immune system.
To characterize the immune response to CrPV in the fly we investigated both humoral and cellular components of the immune system.
Both in vitro and in vivo animal and human studies demonstrate age-related declines in both humeral and cellular components of the immune system (9 ).
Taken together, the favourable interaction observed with the PDT and OV combination treatment is likely related to effective targeting of both vascular and cellular components of the tumour.
The results of the present study indicate a hypercoagulable condition in the dexamethasone-treated group (increase in alpha angle and MCF with a reduction in CFT on all profiles; decrease in CT on the in-TEM® profile), with the involvement of both plasma and cellular components of hemostasis.
Although atherosclerosis is initiated by the exposure to traditional lifestyle risk factors, inflammation is a key driving force at each stage of atherosclerosis development [ 43], with both innate and adaptive cellular components of inflammation involved in disease progression.
Breast carcinoma is accompanied by changes in both the acellular and cellular components of the microenvironment, the latter typified by a switch from normal mammary fibroblasts (NMFs) to myofibroblasts during cancer progression.
This cytokine family regulates immune functions of cellular components of both innate and adaptive immune systems, including dendritic cells, T cells, B cells, and natural killer cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com