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Although strain increased MMP-2 activity for both cell types, this trend was significant (p ≤ 0.05) only for HAVICs.
In both cell types this knockdown resulted in decreased Aβ inhibition of NO induced cGMP accumulation (Fig. 3A, B).
In both cell types this was due to increased apoptosis, demonstrating that IGFBP5 functions as an anti-apoptotic, pro-survival factor in these two pro-fibrotic cell types.
In fact, DCs and NK cells can interact with each other, and depending on the activation status of both cell types, this reciprocal dialog may lead to NK cell activation, DC activation, or apoptosis [ 65].
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Using this system, we showed that U87 mg and DAOY cells have opposing electrotactic responses cathodal and anodal, respectively when plated as 3D spheroidal aggregates, and both cell types maintain this response for at least 24 h.
Thus differentiation, or (more broadly) fate specification, is required to maintain the expression of the oncogenic signaling pathway, and is likely to drive the retention of both cell types in this basaloid tumor type.
Therefore, it makes sense that both cell types express this gene similarly.
Total 53BP1 foci numbers were similar (∼100 foci per nucleus) in both cell types at this time point.
Translocation of Bax from the cytosol to mitochondria was observed in both cell types, and this preceded cytochrome c release in both T47D and MCF-7 cells.
As shown in Figure 1, overexpression of HMGA1 considerably increased RBP4-Luc activity in both cell types and this effect occurred in a dose-dependent manner.
Periprocedural administration of the STAT-1 dODN reduced the infiltration of both cell types at this point underlining not only its inhibitory effect on cellular rejection per se but also that early rather than late changes in pro-inflammatory gene expression are decisive for this to occur.
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