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Adhesion indices on the other hand were reduced in both cell types, indicating that raft disruption impairs this key step in parasite active invasion of host cells.
At the 24 hours time point the [Ca2+]i level was increased in both cell types indicating that the Tg treatment was efficient.
Strikingly, there was a large overlap in the drugs identified that attenuate infection in both cell types, indicating pathways utilized by the virus in both mammals and insects (p<10−16; Figure 2E).
Induced p53 protein levels were comparable in both cell types, indicating that p53 can be stabilized in senescent cells in a similar way as in early passage cells.
By contrast, Flu (20 μM) reduced gp91 phox expression in both cell types, indicating suppression of ROS generation after Flu treatment.
As shown in Fig 2C, BafA treatment of resting (non-starved) WT and Ctns −/− fibroblasts caused accumulation of LC3B-II in both cell types, indicating that Ctns −/− cells have functional fusion and degradation of the autophagic content.
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Fragmentation in both cell types indicates that conventional mitochondrial fusion depends on the combined actions of MFN1 and MFN2.
Similar responses to free LPS and S. Typhimurium of both cell types indicate that LPS is one of the dominant antigens of S. Typhimurium.
These in vivo tumorigenesis studies for both cell types indicate that Brca1 cells bearing distinct cancer stem cell markers are enriched at least 50-fold to 100-fold in tumor-initiating cells.
The mean square error of prediction for each of the methods and fitting data for both cell types indicate that increasing the number of points reduces the mean square error.
GF120918 treatment reduced the number of intracellular vacuoles by 50% in both host cell types, indicating that host P-gp is not involved in parasite invasion (Fig. 1B, white bars).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com