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TGF-β activation, observed induced by prenatal infections, oxygen exposure as well as long- or even short term ventilation as observed in newborn mice, induces apoptosis and alters both cell proliferation and migration [15].
Therefore, our in virtuo experimentation clearly demonstrated that both cell proliferation and migration are crucially important for re-epithelialisation particularly fore-epithelialisation particularly
Similarly, with adenovirus overexpression of sEH, both cell proliferation and migration rates were reduced by 31.4% and 45.8%, respectively.
Besides JNK, we also looked into other molecules downstream of Rac1, which are involved in both cell proliferation and migration.
There was no gene whose two or more siRNA inhibited both cell proliferation and migration by >30% (data not shown).
In addition, both cell proliferation and migration were measured in a concentration-response curve in presence of NECA.
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This occurs due to both cell proliferation and cell migration from adhesion to suspension.
The development of ASP relies on both cell proliferation and cell migration [29], [30], [31].
By regulating both cell proliferation and cell migration, miR-965 contributes to the robustness of this morphogenetic system.
We hypothesized that IL-1 and TNF-α suppress cellular proliferation and migration of both inner and outer zone meniscal cells, while TGF-β1 enhances cell proliferation and migration of both inner and outer zone cells, in cell and tissue models of meniscal repair.
Integrins are heterodimeric cell surface receptors comprised of α and β subunits that mediate endothelial cell proliferation and migration, both crucial features of neovessel establishment (Brooks et al, 1994a, 1994b; Brooks, 1996; Mitjans et al, 2000).
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