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PLEKHF1, CCNE1, C19orf2 and ZNF536 were slightly up-regulated by cisplatin treatment in one or both cell lines however siRNA knockdown was still effective (Figure 2B).
CXCR4-overexpression in both cell lines, however, promoted a CXCL12-dependent chemotaxis, thereby demonstrating that in both cells lines ligand-bound CXCR4 can elicit a motility phenotype.
Cr VI) exposure induced a significant increase in chromatid breaks in both cell lines, however, the break incidence in exposed shWRN cells was significantly higher than in exposed shCtrl cells (3.4-fold) (Figure 6B).
At a higher concentration (250 µM) of 3O-C12, sincreasescreases in Δ[Ca2+]i were observed in both cell lines, however [Ca2+]i returned to basal levels in C38 by the 20 min mark but remained elevated in IB3-1 for the duration of the time course (Figure 3B).
Sorafenib also caused an increase in NOXA expression in both cell lines, however, to a lesser extent.
The results showed that eIF5A-2 was expressed in the control cells of both cell lines; however expression was higher in NCI-H1299 comparedmpared to A549 cells.
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Both tumor cell lines, however, have a highly methylated FAS promoter, and therefore, an inhibited FAS expression.
We have observed that after treatment with epigenetic drugs, the level of transcript expression of MBDs has consistently increased for every drug treatment in both the cell lines; however DNMTs exhibit decrease in expression in comparison to untreated cells after treatment with SFN.
Both of these cell lines, however, have been derived from dog kidneys.
No ANT1 mRNA is detectable from both breast cancer cell lines, however, indicating the majority of ANT proteins in breast cancer cell lines might be ANT2 proteins.
No Cl− currents were activated by FasL in both Scott lymphocyte cell lines, however, Scott cells still showed Fas receptor-induced PS exposure, which could be prevented by caspase inhibition and hence was apoptosis-induced.
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