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This global view of both cell lines enables the comparative study of the metabolic connectivity.
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The information of high frequency dielectric properties of different types of cell lines enables the detection and signature identification of cells in a microfluidic device at microwave frequencies.
The use of cell lines enables to work with relatively high numbers of hypoxia-selected cells and to reduce the complexity of system, as exogenous cytokines are necessary to support survival and growth of primary cells.
Additionally, a hybridoma clone in murine or hamster cell lines enables large-scale production at low cost, as recently reviewed by Yamada [ 30].
Analyses of the glycoproteins residing at the cell surface, in both tissues and cell lines, enabled discovery of cell-membrane markers that may be shed and released into the peripheral circulation.
The simplicity of the CRISPR/Cas9 system of genome engineering has opened up the possibility of performing genome-wide targeted mutagenesis in cell lines, enabling screening for cellular phenotypes resulting from genetic aberrations.
Reporter cell lines enable the fractioning of hESC populations based on endogenous gene expression.
Transgenic and knockout mice provide syngeneic (or congenic) models for CSC research, as they allow to establish cancer diseases in immune-competent animals that mimic the corresponding human situation, and are a source for cell lines enabling studies of CSC properties.
Furthermore, cell lines enable the study of a single cell type at a time, while the human placenta consists of many cell types.
These cell lines enable us to study the differential function of ERs in tumor cells under controlled and well-described conditions.
The natural variation in Msi levels across breast cancer cell lines enabled a comparison of splicing patterns between Msi-high (luminal) vs Msi-low (basal) cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com