Sentence examples for both cell lines despite from inspiring English sources
An interesting observation was made when we considered proteins that were only altered in both mES_14_Mono and mES_14_Tris: Two thirds of them showed the same change tendency, i.e., either up-regulated in both cell lines, or down-regulated in both cell lines, despite opposite gene dose alteration (trisomy versus monosomy).
As expected, the treatment with TGF β1 increased stress fiber in both cell lines despite their different cell cell dispersion.
Following Hsc70 silencing using two shRNAs (Fig. 2a ii), cell number was reduced by 80% in both cell lines despite a significant upregulation of Hsp72 (Fig. 1a).
There was an increasee in MIF protein levels in both cell lines, despite constant (LN18) or even decreasing (LN229) mRNA levels with higher cell density.
Matrix mineralization was increased more than twofold in MT2A-overexpressing cells compared with parental cells in both cell lines despite their different basal differentiation stage (Supplementary data 2D and E).
However, within this model, LBH589 demonstrated comparable effects upon HIF dependent reporter expression in both cell lines, despite eliciting comparatively greater suppression in UMRC2 as determined by qRT-PCR.
S405/418 phosphorylation was maintained in the 85 kDa cortactin form in both cell lines following serum starvation, despite of the lack of ERK1/2 activity (0 min, Figure 3A and Figure 3B).
The results clearly demonstrate that cyproheptadine has similar cytotoxic effects in both HCC cell lines despite their different p53 genetic backgrounds.
It is noteworthy that there was only a mild effect of erlotinib at a physiological dose in both cell lines (see Figure 2A and B) despite strong downregulation of p-AKT in GLC-4 cells and p-ERK in VL-68 cells (see Figure 3C).
Despite these differences, both cell lines showed similar apoptotic responses to doxorubicin as indicated by cleavage of caspase 3.
Despite these changes, both cell lines sustained relatively unaltered mitochondrial respiration.
