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Exponentially growing U937 and K562 cells and freshly collected normal lymphocytes at a cell density of 1 × 106/ml were incubated with different concentrations (1 5 μg/ml for U937 cell and 0.5 2 μg/ml for K562 cell IC50 dose of both cell line and imatinib mesylate (10 μg/ml for normal lymphocytes)) of GNP-NKCT1 (I, II, and III) for 24 and 48 h at culturable conditions at CO2 incubator.
The residual biotinylation reagent was quenched with 10mM Lysine in both cell line and ascites preparation.
The microscope operator was blind to both cell line and treatment condition.
LY294002-mediated effects on GLUT1 appeared both cell line and condition dependent.
RARβ is a known tumour suppressor in breast cancer [ 24, 27], confirmed in both cell line and animal models.
For intracellular accumulation and cellular efflux assays, two-way analysis of variance (ANOVA) was used to assess both cell line and inhibitor effect.
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Most of the compounds showed potent activities against both cell lines and specific kinases.
Some of the compounds showed significant activities against both cell lines and VEGFR.
BSA decreases nanoparticle internalization in both cell lines and protects the iron core once they have been internalized.
A small-molecule inhibitor of YES1 impeded the proliferation of β-catenin-dependent cancers in both cell lines and animal models.
In conclusion, l-pNIPAM hydrogel scaffolds supported both cell lines and induced formation of villus-like structures when cells were layered on and cultured under dynamic conditions.
More suggestions(16)
both cell type and
both base line and
both cell viability and
both cell density and
both cell apoptosis and
both cell adhesion and
both cell delivery and
both cell wall and
both cell positioning and
both cell death and
both cell surface and
both command line and
both cell culture and
both cell adherence and
both staple line and
both germ line and
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