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Both cell alignment and elongation increase with increasing aspect ratio, and even a shallow grating (aspect ratio of ∼0.05) is sufficient to induce 80% cell alignment.
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The depth and width of the polystyrene gratings both show strong effects individually on cell alignment and elongation that are qualitatively similar to the results of other studies.
Both micro- and meso-scale architectures directed cell alignment and resulting tissue organization, and when combined, meso cues could enhance or compete against micro-scale cues.
In order to improve cells infiltration into the fibers network, direct electrospinning of a 3D aligned nanofibrous tube has been realized, promoting cell alignment and myotube formation [101].
Abnormalities in cell alignment and fiber orientation were also observed in both ventricles.
The composite scaffolds exhibited good biocompatibility and facilitated cell alignment and proliferation in vitro.
Fb-free MP films were not effective in cell alignment, and clumps were formed.
3D micropatterned scaffolds can promote cell alignment and muscle tissue formation.
Finally, Figure 7f indicates the highest degree of cell alignment and, most of the cells are nearly parallel.
Cells cultured on substrates with smaller pitches exhibited a substantially higher frequency of cell alignment and smaller circularity index.
Histological analysis 6 weeks postoperatively showed no fibrosis or encapsulation but instead longitudinal cell alignment and axonal regrowth.
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CEO of Professional Science Editing for Scientists @ prosciediting.com