The break points are no more.
Then, two large break points are selected for design basis accident analyses.
The break points are then selected based on a score function that prefers less crowded areas, noticeably away from junctions.
The break points are based on the CLSI guidelines (7 ).
Clinical Laboratory Standards Institute break points are not established for AZM.
Fusion break points are assessed by de novo assembly using GapFiller (Nadalin et al., 2012).
These break points are similar to those found in at least 6 reported cases with der(3 t(1;3) (Table 1) [ 5- 7].
The majority of break points detected in this study are "clean" break points, where the sequence near the break point shows few differences from the reference, which suggests that these break points are the result of illegitimate recombination events.
(b) A double crossover is a locus where two break points are separated by less than 5000bp and are separated by at least 6 markers.
The results show that a disproportionate number of events are predicted in repetitive regions: only 13% of the somatic break points are not affected by repeats.
