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Only one humanized version was tested and it retained the in vivo and in vitro properties of the parental antibody, suggesting that humanization guided by both biological and sequence information allows for retention of full antibody activity.
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Geminivirus species demarcation is based on both biological characteristics and sequence relatedness [ 1, 32].
We have studied how to represent biological sequences and sequence-related genomics concepts using logical data structure.
MAKER2 provides both a conservative biological sequence (transcript and homolog) alignment-based set of gene models that best agree with transcript and protein homolog alignments, and a set of ab initio gene predictions that do not overlap the biological sequence alignment-based set.
Subsequently, we apply the method to simulated and biological sequence data and discuss the results.
The combination of Oligo-Analysis and pNO results also revealed a difference between biological and non-biological sequences.
Uncertainties in the distribution of deaths by anatomical position and biological sequence of the injury, therefore, remain unresolved.
We show that the approximations inherent to the WLS method did not affect negatively the accuracy and reliability of the test both in the analysis of biological sequences and DNA-DNA hybridization data (for which character-based testing methods cannot be used).
We have specified formats for biological sequences, sequence annotations and alignments and references to data and resources.
The researchers began by sequencing each patient and both biological parents — what's known as a parent-child trio.
SO is designed to describe biological sequences including located sequence features, for example, polymorphisms, polypeptide domains and predictions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com