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This means that the heterodimer is better in terms of both binding specificity and affinity, as compared to either homodimers.
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It is well known that electrostatic interaction could distinctly influence on both the binding specificity and affinity of a protein with substrates.
Both receptor binding specificity and virus infectivity are key factors in determining whether influenza A virus becomes pandemic.
Synthetic small molecule antagonists exist, including a xylyl bridged bicyclam AMD3100, which have been shown to have both a high binding specificity and an effective inhibitory action against a number of disease states including arthritis, cancer and HIV infection.
We also noticed that the binding affinity we studied here does not equal to binding specificity, and both of them may play important roles in the evolution of Dscam.
Further, the BsAb retained the antigen binding specificity and the receptor neutralizing activity of both of its parent antibodies.
In vitro binding and specificity were assessed for 125I-Fab, and binding, specificity and internalization were assessed for 111In-Fab using both H314 and A431 cells.
The link between determining binding specificity and finding sites where the transcription factor is likely to bind is the way in which binding specificity is represented.
Based on the other HLA binding specificity and population coverage, seven novel promiscuous epitopes were identified.
Results are discussed in terms of receptor binding specificity and the molecular modeling protocol used.
Here, we report a unique binding specificity and mode of ligand binding for a family 32 CBM.
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