Sentence examples for both binding functions of from inspiring English sources

Hence, the contrasting binding thermodynamics of bH1 antibodies compared to Herceptin is consistently demonstrated in both binding functions of many bH1 variants.

The protein acetylation and protein binding functions of p300/CBP are intricately interrelated, and both are targets of pharmacological interventions that may have considerable therapeutic applications.

These data were consistent with the role of c-Src in EGFR activation and suggested that both tyrosine kinase activity and protein binding function of Src are essential for cell surface GRP78 induced EGFR activation.

We report here, for the first time, that the ligand binding function of human serotonin1A receptors exhibits an increase in membranes isolated from cholesterol-depleted neuronal cells.

siRNA knockdown-rescue experiments demonstrated that these three amino acid residues are crucial for the leader RNA binding function of P protein in the CHPV life cycle.

These data suggested that "TGG" might contribute the binding function of M1 more significantly.

The binding function of purified receptors can be assessed with radioligands, but the interaction of receptors with their biochemical effectors has not been amenable to direct study.

Therefore, one role of DevRN is to mask the intrinsic DNA binding function of DevRC.

Thus, the PAS domain is not necessary for the E-box binding function of the Arnt homodimer.

This complex localizes to the sites of DSBs where the DNA binding function of RAD50 and the nucleolytic activity of MRE11 contribute to DNA repair, by both homologous recombination and non homologous end-joining.

Although these results propose an RNA binding function of yeast eIF3b-RRM, determination of its exact RNA target is out of the scope of this work.