Sentence examples for both binding and specificity from inspiring English sources
Fluorescent intensities associated with the cells were compared using fluorescent microscopy, and the data was evaluated for both binding and specificity.
Thus, for proteins with multiple conformations that are close in energy, such as many intrinsically disordered proteins, residues distant from the active site can alter both binding affinity and specificity.
Overall, we observed that the K0.5s of sugars for E457Q-hSGLT3 resembled those of hSGLT1 more than hSGLT3, along with changes in specificity, namely an increased selectivity against imino sugars and for 3DO-glc, indicating the remarkable role of amino acid 457 in determining both binding affinity and specificity in SGLT proteins.
By projecting quantum chemical similarities onto orthogonal (independent) factors, it was possible to uncover parameters of both binding Efficiency and Specificity to open new perspectives on the molecular properties of auxins.
Molecular characterization of the critical contacts for successful binding and specificity.
In vitro binding and specificity were assessed for 125I-Fab, and binding, specificity and internalization were assessed for 111In-Fab using both H314 and A431 cells.
The combination of these three interactions is likely to ensure both stronger binding and higher specificity.
Considering proton coupled peptide symport within the POT family, a picture emerges from our study whereby substitutions of conserved residues in the N-terminal domain affect aspects of both proton binding and peptide specificity.
Optimizing these inhibitors to improve both Plk1 PBD-binding affinity and specificity would be necessary in order to use them in preclinical and clinical studies.
It is well known that electrostatic interaction could distinctly influence on both the binding specificity and affinity of a protein with substrates.
