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Interfering with protein protein interactions is an important aspiration in both basic and disease biology but small molecule inhibitors have been difficult and expensive to isolate.
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Translational science drawing on the opportunities outlined here will require investment in both basic and applied disease research.
Utilizing these samples for diverse research questions in both basic and clinical studies of glomerular disease could help to advance the understanding of glomerular disease pathogenesis [ 1].
Its health system is basic and disease is widespread.
A key component of using hiPSCs to elucidate basic and disease relevant mechanisms is the ability to direct the differentiation of stem cells to specific neuronal cell types.
In the past few decades, increases in the incidence and prevalence of asthma worldwide have resulted in increased morbidity and mortality and have sparked renewed interest in both basic and clinical research related to this disease.
Research on animal models has brought numerous powerful and valuable insights to both basic human biology and disease pathology [ 34- 36].
There is a great potential for applying these discoveries to our comprehension of both basic immune physiology and disease pathology.
For these reasons, genetically modified animals expressing one or more disease genes are a vital resource for both the academic and private sectors, and are an indispensible research tool for advancing our understanding of both basic biology and human disease.
Open image in new window Figure 1 Basic information and disease association of human monocyte proteins.
Basic demographic and disease characteristics were collected prior to distribution of the self-administered questionnaire.
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