Sentence examples for both basal levels of from inspiring English sources

[11C]Raclopride ([11C]RAC) is a selective dopamine D2/D3 antagonist that is commonly used in positron emission tomography (PET) studies to assess both basal levels of receptor availability and changes in availability caused by alterations in striatal dopamine concentration.

Transfection with si-p27Kip1 abolished both basal levels of p27Kip1 and salinomycin-induced p27Kip1.

Since Pgp is constitutively expressed on lymphocytes from RA patients, and its expression is correlated with disease activity, both basal levels of expression and upregulated levels upon long-term administration could be limiting factors in sustaining long-term efficacy [ 56].

H2O2 stimulation resulted in an increase in Nrf2 stability (2.4 ± 0.2-fold) in random oligonucleotide (RO) transfection controls whereas HDAC2 KD showed a significant reduction of both basal levels of Nrf2 (0.5 ± 0.0-fold; p < 0.05) and H2O2 stimulated Nrf2 (1.5 ± 0.3-fold; p < 0.05) compared with RO controls (Fig. 2G).

CXCL10 augmented the expression of RANKL by 62.6%, and PTX inhibited both basal level of RANKL (from 37.4 ± 16.0 to 18.9 ± 13.0%) and CXCL10-induced RANKL expression in Jurkat T cells (from 100% to 48.6 ± 27.3%).

Figure 6 shows that CXCL10 augmented the expression of RANKL more than twofold and that PTX inhibited both basal level of RANKL (from 37.4% ± 16.0% to 18.9% ± 13.0%) and CXCL10-induced RANKL expression in Jurkat T cells (from 100%to48.6%6% ± 27.3%).

The effects of CK2 on IL-6−induced Twist expression were further confirmed by knockdown of the catalytic subunit CK2α in SCCHN cell lines, in which both the basal levels of Twist expression and those after IL-6 treatment were reduced (Figure 2F).

These results should indicate the extent to which host genotype influences both the basal levels of these traits and their levels in response to exposure to pathogens.

8 Both high basal levels of income and elevated economic growth have been found to be associated with reduced suicide rates.

For Pax6, on the other hand, we found a significant increase in H3-K27me3 both upstream of the first TSS and downstream of the second TSS (p<0.01 in both cases), whereas basal levels of H3-K27me3 upstream of the second TSS were much lower and did not show any statistically consistent change during the first eight days of differentiation.

Both cell lines had higher basal levels of autophagic activity than HEK293T cells, as demonstrated by the presence of a small number of eGFP-LC3 puncta in 30%40%% of cells expressing the empty vector (Fig. 2A and 2B).