Sentence examples for both amplification and mutation from inspiring English sources

In contrast, EGFR is the predominant receptor tyrosine kinase targeted by both amplification and mutation in adult GBM [ 25, 47].

For example, breast tumors show mutation or loss of PTEN or both, amplification and activating mutations in PIK3CA, amplification of Akt2 and p70S6kinase, and overexpression of Akt3 [ 11].

EGFR has a direct role in inflammation and subsequent immunosuppression and both its amplification and mutation have been frequently observed in glioblastoma tumors (57).

These include AR gene amplification and mutation.

Consequently, amplification and mutation can be achieved rapidly in a single step.

EGFR phenotypic changes in GBM can occur by overexpression, amplification, and mutation.

To overcome this obstacle, several selective CYP21A2 gene amplification and mutation detection procedures are developed [ 12- 17].

Frequent concurrent amplification and mutation of PIK3CA in human breast cancers.

Protocols for PCR-based amplification and mutation analysis of exons and exon-intron boundaries were as previously reported [ 17].

Amplification and mutations of AR gene are identified as critical factors related to the poor prognosis of prostate cancer.

We revealed a strong inverse association between 20q amplification and mutations in the PI(3)K pathway.