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The finding that peptides modulated both aggregation of cells and cell surface amyloid levels in parallel was also consistent with amyloid dependence of aggregation.
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Interestingly the bacterial cells grown in high C/N ratio medium showed aggregation of cells evidenced by the significantly higher cell aggregates.
One of the important aspects during biological clogging in trickle-bed bioreactors is the aggregation of cells and the detachment of cells and aggregates from pore bodies within the porous bed.
The aggregation of cells by Abs and the tightness of the aggregates was dependent on the particular cell line as well as on the Abs used.
We further tested the effect of chloroquine on development by examining the aggregation of cells in submerged culture and found that tpp1− cells aggregated more slowly than wild-type cells in the presence of chloroquine (Fig. 7B).
Only subtle changes in cell cycle distribution were observed following siWee1 transfection, with a minute aggregation of cells in late-S compared to the control cells in both SW-954 and CAL-39 cells.
And also, these membranes showed good growth of NIH/3T3 fibroblast cells although a little aggregation of cells was observed.
The aggregation of cells was found to be dependent on the initial cell density, as well as the mesh size of the hydrogels.
Since the aggregation of cells into clusters is a universal biological process, these findings and scaffolds can be applied to many other relevant cell types.
The aggregation of cells that were exposed to β-sitosterol and epigallocatechin was reduced from 25 μm as observed in untreated cells to < 10 μm in length.
The aggregation of cells in TMC20 hydrogels resulted in enhanced cartilage matrix production compared with their PEG20 counterparts over 3 weeks of culture.
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