Sentence examples for both agents significantly improved from inspiring English sources

However, both agents significantly improved symptoms of OAB from baseline as evaluated by the 3 outcomes measures (p < 0.001).

Both agents significantly improved event-free survival in 6/6 osteosarcoma xenografts in vivo as single agent therapy, but produced no objective responses [312], [313].

Neither the PI3K inhibitor BKM120 nor the MEK inhibitor PD0325901 given as single agents significantly improved mouse survival.

4 Although aTNF agents significantly improve clinical symptoms in patients with AS, 9 16 approximately 40% of patients do not respond adequately, and there is no evidence of inhibition of radiographic structural damage with aTNF agents.

The bonding agent significantly improved the flexural bond strength between the ceramic and the gold alloy, but had no influence on the Co-Cr alloy.

O6-BG, as a single agent, significantly improved survival of the CHLA-136 xenografts (P=0.007).

This agent significantly improved functional class status and time to clinical worsening compared with placebo.

First, our results demonstrate that the use of Tween-80, an emulsifier and dispersing agent, significantly improved the actual concentration of freshly prepared solutions of capsaicin compared to solutions not containing Tween-80.

Perifosine is an alkylphospholipid inhibitor of the PI3K/AKT pathway, which when used as a single agent, significantly improved the survival of mice bearing human neuroblastoma xenografts (AS, NGP, BE2, and KCNR) [94], and showed synergistic effects in combination with etoposide [95].

When given in combination with capecitabine, this agent significantly improves time to progression [ 8].

Trastuzumab and newer anti-HER2 targeting agents have significantly improved the clinical outcomes of patients with HER2 positive MBC.