Sentence examples for both active sites of from inspiring English sources

Also, it was concluded that in order for the compounds to be active, they must bind with both active sites of HNMT enzyme (two pockets) to inhibit it.

According to molecular docking studies, all compounds exhibited high affinity and good amino acid interactions similar to AAZ on the both active sites of hCA I and hCA II enzymes.

Furthermore, in the external aldimine model of N-succinyl-2-amino-6-keto-pimelate, the succinyl group overlaps with a glycerol binding site that has also been identified in both active sites of the Mtb-DAP-AT dimer.

Recently, Sachdeva et al. have postulated that the overall reaction may occur simultaneously in both active sites of the dimer [24].

Unlike the previous structure, FAD is seen occupying both active sites of the homodimer.

In the presence of GSH, both active sites of PDI remain in the reduced form.

We agree with the reviewer on the question of whether both active sites (DnaQ-H and MAEL-specific activities) can be realized in the same protist MAEL domain.

Simultaneously, every step in that procedure was applied on a plant PARP enzyme to investigate the differences of both active sites.

Alternatively, it could alter the nucleotide state of both active sites.

The binding of a corrin to CobR induces global electronic changes within the protein, which alter the properties of both active sites across the dimer.

Thus, although the mechanisms differ somewhat for each active site, the substrate-binding loops of both active sites are prevented from inserting into the interface because the interface is occupied by segments of IL-A and IL-B.