Sentence examples for both activation and repression from inspiring English sources

GLI1 has activation properties whereas GLI2 and GLI3 have both activation and repression activities [reviewed in [ 4]].

Gene expression studies of individual brain regions have reported that Mecp2 loss-of-function leads to both activation and repression of its gene targets in mice.

We investigated how sites for the transcription factor CRX encode both activation and repression in photoreceptors by assaying thousands of genomic and synthetic cis-regulatory elements in wild-type and Crx−/− retinas.

Therefore kis may be involved in both activation and repression.

Similarly, PABPC1 is involved in both activation and repression of translation at the level of initiation.

Culi and Modolell (1998) obtained evidence for a role of these sequences in both activation and repression of sc.

For example, the recently identified lincRNA-Cox2 mediates both the activation and repression of distinct classes of immune genes [ 25].

Although we observed both the activation and repression of distinct sets of genes in the absence of Arx, our data indicate Arx functions primarily as a transcriptional repressor in the ventral forebrain.

Therefore AmrZ is an atypical RHH protein possessing both transcriptional activation and repression activity.

However, both the activation and repression activities of LXR were completely abolished in DNA binding domain- (DBD), ligand binding domain- (LBD) or AF2-deletion mutant cells.

The transcription factor E4BP4, also known as NFIL3, has been known to have both transcription activation and repression activities [ 34, 35].