Sentence examples for both activation and expression from inspiring English sources

Thermogenesis in BAT is achieved by adrenergic-stimulation of both activation and expression of uncoupling protein 1 (UCP1) in the mitochondria.

While miRNAs down-regulate gene expression mostly by destabilization of target messenger RNA [ 8], the regulation of gene expression by lncRNAs appears to be much more complex, involving both activation and repression of gene expression, and modulation of chromatin architecture [ 9].

For example, both activation and repression of p107 expression or p107 reporter plasmids are mainly, but not exclusively, regulated through the distal E2F site [23].

Recent studies suggest that Myc acts as a widespread regulator of gene transcription [13], [14], and both activation and repression of gene expression contribute to the Myc-induced epidermal phenotype [15], [16], [17].

MeCP2 is a transcriptional regulator involved in both activation and repression of gene expression.

p63 has been shown to target different types of regulatory regions (such as promoters and enhancers) and involved in both activation and repression of gene expression [ 33– 33].

Identification of a group of genes that show both activation and repression depending on Oct3/4 expression levels provides a possible mechanism for the requirement of appropriate Oct3/4 expression to maintain undifferentiated ES cells.

Ss::Tgo heterodimers target gene expression (both activation and repression) through the XRE motif both in vitro and during development [16], [19].

DNA methylation has been associated with both activation and repression of the gene expression.

The ability to control gene expression by both activation and repression is a useful method to discover biological function.

Alternative promoters with ability to control gene expression by both activation and repression independent of nutritional state are thus desirable in these cases.