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This study was the first to identify SUA as both a time dependent co-variant risk factor for overall cancer incidence and one exhibiting a clear dose response to baseline SUA.
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In this study we report for the first time the presence of Ang-(1 12) in neonatal cardiac myocytes from both WKY and SHR together with a time dependent intracellular incorporation of labeled Ang-(1 12) in both strains.
Both are analyzed by means of a time dependent large eddy simulation in this paper.
The digestion with trypsin gave multiple bands with both the forms of MtbMfd in a time dependent manner but monomeric fraction showed more sensitivity (Fig. 6A).
Flow cytometric assays suggested that 7a induced Hela cells to arrest in G0/G1 phase both in a time-dependent and dose-dependent manner.
However, the MPO/H2O2/SCN− system induces both a time-dependent loss of activity, and a greater overall extent of inhibition with identical oxidant concentrations.
We found that PTH reset the circadian rhythm of the Per2::Luc activity in the femurs in both a time-dependent and a dose-dependent manner.
- In our study, we demonstrated that salinomycin could upregulate ER stress-related proteins such as phospho-EIF2A, ATF4, DDIT3 in both a time-dependent and dose-dependent manner in human NSCLC cells.
In the suprachiasmatic nucleus, a light pulse induces Per1 and Per2 mRNA expression and resets the circadian clock in both a time-dependent and an intensity-dependent manner (Shigeyoshi et al. 1997).
Increased peroxidase activity obtained in shoot and root tissues of chickpea seedlings exposed to solutions B and C may indicate an elevated level of ROS production in those organisms in comparison to that of the control and those treated with solution A. POD activity increased both in a time-dependent and dose-dependent manner.
Accordingly, 4HPR (10 μM) triggered apoptotic cell death (26% after 48 h of treatment) and over-expression of Uba80 and Uba52 in Hep3B cells, both in a time-dependent manner, accompanying increased poly(ADP-ribose polymerase (PADP-ribose polymerase
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