Sentence examples for both a prognostic factor from inspiring English sources
Two thirds of the participants thought that QoL was both a prognostic factor and the secondary endpoint in digestive oncology clinical trials, whereas only half of them thought it would be relevant to evaluate its surrogacy.
Methylguanyl methyltransferease (MGMT) was the first molecular marker to serve as both a prognostic factor and a target for personalized therapy [ 2], and therapeutic resistance in MGMT-unmethylated tumors has emerged as an important clinical issue.
TP53 has been investigated as both a prognostic factor and a predictor of the response to therapy, but with conflicting results, as the study design made it difficult to draw firm conclusions [ 27, 33- 35].
For example, among people with atrial fibrillation, age influences both response to warfarin and risk of stroke, and so is a both a prognostic factor 3 and a factor that predicts differential treatment response.
Over-expression of the human epidermal growth factor receptor 2 (HER2) in breast cancer was recognized in the 1980s and provided both a prognostic factor and a predictive factor [ 5].
TS expression has been extensively studied in the last few years both as a prognostic factor and as a predictor of response to chemotherapy.
The study by Schatz et al. [ 44] observed that it is important to measure FEV1 regularly during pregnancy, both as a prognostic factor for perinatal outcomes and as a measure of asthma control.
Two studies with multivariate analysis found tumour site to be a prognostic factor, both with some methodological limitations.
In the majority of studies with Ki-67 as a prognostic factor, both node negative (pN0) and node-positive (pN+) patients were included.
The quality of surgical excision is increasingly being recognised as a prognostic factor both in rectal cancer (Quirke et al, 2009) and colonic cancer (West et al, 2008; Hohenberger et al, 2009).
In the present study, however, lactate was a prognostic factor for both definitions and reclassified some Sepsis-3-defined patients when its levels were above 4 mmol/L.
