Sentence examples for both a dramatic reduction from inspiring English sources

As we have already demonstrated, a zTERT knockdown induces both a dramatic reduction in the number of circulating blood cells and an inefficient developmental hematopoiesis, concurrent with the inhibition of telomerase activity in zebrafish in vivo, but in the absence of detectable telomere length alterations.

Similarly, JQ1 treatment induced both a dramatic reduction of tumour load in a primary ALL xenograft model created from a high-risk primary B-precursor ALL (ALL-105) and extended event-free survival (⩾25%hCD45++ cells in peripheral blood) by at least 24 days (Supplementary Figure 1B).

When these structural changes were both introduced, a dramatic reduction of activity was observed for both N1 and N3.

Knocking out two different variants of the calcineurin catalytic subunit A (A α and A β) both led to a dramatic reduction in slow fibre type and oxidative enzymes.

Blocking both the 5' and 3' junctions resulted in a dramatic reduction in D-loop disruption (Fig. 7A), indicating that the streptavidin-biotin complex effectively blocked WRN recognition of the junctions.

Furthermore, both cell populations showed a dramatic reduction of pAkt levels.

In both cases, there was a dramatic reduction in the survival of transgenic hybrid individuals carrying the dwarfing gene.

For instance, in the central domain both ΔNArm1 155 and ΔNArm1 128 caused a dramatic reduction in endogenous Armadillo levels, with decreases of 60 and 67% respectively (Figure 12).

An increase in temperature causes a dramatic reduction in both the storage and loss moduli.

The results showed that high temperature reduced root lodging resistance significantly, as indicated by a dramatic reduction in both root anchorage and safety factor (against anchorage failure).

In high-fat fed Ldlr−/− mice, the addition of nobiletin resulted in a dramatic reduction in both hepatic and intestinal TG accumulation, attenuation of very low-density lipoprotein(LDL -TG secretion and normaLDL -TGn of insecretionsitivity [40].