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This finding suggests a dual-layered mechanism of transcriptional regulation, comprising both a continuum of binding-site occupancy by each PIF and a superimposed layer of local regulation that acts differentially on each PIF, to modulate its intrinsic transcriptional activation capacity at each site, in a quantitative pattern that varies between the individual PIFs from gene to gene.
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Both also host a continuum of mark-making practices, from informal graffiti to monuments aspiring to direct national narratives.
Both types exist on a continuum of innovation possibilities that differ in how closely they resemble the existing product.
Although 5XFAD dystrophic neurites generally could be classified as either Type I or Type II, we observed that some dystrophies contained variable mixtures of vesicular structures found in both subtypes, suggesting that a continuum of neuritic morphologies might exist between Type I and Type II neurites.
For all networks and the system as a whole, we observed a continuum of both specificity of associations and impacts (Figure 1), which indicates that contrasting host exploitation strategies (i.e. integrating the number of host isolates, the impact achieved on each, and phylogenetic relatedness between hosts) co-occur within our communities.
When artists are studied more carefully, certain personality characteristics appear to reside upon a continuum of both normal behavior and psychopathology.
There is a continuum of both sequence and amino acid divergence between definite heteroplasmy (e.g., H. fuscipennis) and definite numts (e.g., H. rugulosus), and due to the high rate of change in mtDNA relative to nuclear DNA, even unusual amino acid changes are not reliable markers- e.g., the coding sequence of H. paradoxicus contains more unique differences than does the numt.
Feng Zhenghu and Chen's cases are both extreme, but they are on a continuum of illegal punishment and detentions for activists that is very, very common in China".
Large vessels grow in both length and breadth, likely requiring a continuum of cell division orientations.
Qualitative descriptions of both variables were transformed into quantitative continuous variables reflecting a continuum of variation.
In human there is a continuum in gene expression (low-medium-high or narrow-medium-broad) that goes hand in hand with a continuum of CpG doublet concentration around TSS and both are reflected in a continuum of nucleotide frequencies (small-medium-large ΔWS).
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