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They also include studies that found either borderline significant reduction in CDI (P=0.04, [ 53]) or no statistical significance through a reduction in either high-risk drugs or total antimicrobial usage in healthcare settings (respectively, P=0.0597 and P=0.0823, [ 52]).
A borderline significant reduction in pain intensity has been demonstrated.
We found a borderline significant reduction in mortality for those who participated in the trial (MRR after 12 months of follow-up: 0.64 (0.64-1.0.64.
A Cochrane review, on the use of elective HFO compared to CMV in preterm infants, found a borderline significant reduction in the rate of chronic lung disease with the use of HFO [ 16].
Self-management was associated with fewer thromboembolic events (RR 0.51, 95% CI 0.37 to 0.69, p≤0.001) and with a borderline significant reduction in all-cause mortality (RR 0.68, 95% CI 0.46 to 1.01, p=0.06) than standard care.
A combined analysis of these trials showed that early BCG was associated with a borderline significant reduction in infant mortality of 21%95%CI -2CI -2%%; 39 %), and a 48%95%95 % CI: 18 %; 67%%) reduction in neonatal mortality, before most children in the control group received BCG [ 10].
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Cells pre-exposed for 16 hours to high T concentrations (200 ng/mL) resulted in a borderline-significant reduction in mTOR phosphorylation compared to non-T exposed (control) cells (p = 0.088, Figure 4B) following 30 minutes of exposure to 100 nM of insulin.
In patients classified as being at low risk for exacerbations, there was a borderline significant reduction with tiotropium in the number of COPD exacerbations compared with salmeterol (RR 0.89; 95% CI 0.76 1.05; p = 0.1768; adjusted annual rates = 0.48 and 0.54 for tiotropium and salmeterol, respectively) (Fig.�� 2).
The trial was not powered to detect differences in clinical outcomes, but we found an unexpected, borderline significant reduction of all cause mortality at term equivalent age in the NIRS group.
Finally, bolus infusion of terlipressin was associated with a significant reduction of the oxygen delivery index and a borderline significant reduction of the cardiac index.
No substantial effect of increased risk of ovarian cancer was seen in the respective ovarian cluster regions of each gene and only a borderline significant reduction of breast cancer risk was seen for BRCA2.
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