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Further metabolic studies should be able to shed more light on the mechanisms of changed glutamine and creatinine metabolism in MS. Phenylalanine CSF concentrations were slightly decreased in patients with active vs. inactive plaques (borderline significance, Tables 2 and 3).
The (presumably inactive, see above) PF10_0124 is borderline in this respect and is classified as non-mitochondrial.
The BMI was highest in the physically inactive group and this was borderline significant [23.1 ±7.9 vs 20.1 ± 5.8 (p = 0.05)] (Table 1).
The GFPd2 activity was statistically significant (P < 0.05) relative to controls and inactive GFPs, while GFPe1 was borderline significant with P = 0.053, likely due to the small sample size (N = 3).
However, they remained except for moderate smokers who were inactive, the association attenuated and was of borderline significance only (HR=1.67 95% CI 0.99 to 2.81).
"Borderline cocky.
Borderline unwatchable.
Borderline irresponsible.
It's borderline controversial.
Borderline actionable subject matter!
She never understood inactive.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com