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The discrepancy may be explained by the fact that many individuals with MetS have borderline elevations in risk factors and thus may actually have either a low or intermediate risk of CVD [ 58].
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In one patient there was borderline elevation of protein.
We have reported previously a reduction in retinopathy and borderline elevation of albumin excretion rate (AER)/albumin-to-creatinine ratio (ACR; a surrogate marker for microalbuminuria) from 1990 to 2002, whereas microalbuminuria declined and then reached a plateau (7).
Generalized Estimating Equations (GEE) were used to examine factors associated with the complication outcomes (retinopathy, borderline elevation of AER/ACR, microalbuminuria, and peripheral nerve abnormalities), while taking into account multiple visits by individual patients.
For example, the tumor cells in a small PNET may express glucagon, resulting in a borderline elevation of glucagon levels; clinically, however, this PNET is classified as non-functioning because the slight elevation of glucagon is not sufficient to cause glucagonoma syndrome.
Although microalbuminuria remains uncommon in this age-group, it is of concern that almost one-third of adolescents had borderline elevation of AER/ACR, especially since we and others have shown previously this is risk factor for future development of microalbuminuria (22).
However, GEE analyses revealed borderline overall elevation of IL-8 in the DM PE+ versus the DM PE- group throughout pregnancy (visits 1 3; P = 0.05).
Other studies in borderline hypertensive individuals detected elevations in circulating anti-endothelial cell IgG and IgM antibodies [ 64– 64].
We hypothesized that any CA 19-9 elevatindicatesates biologically borderline resectability.
Then again, that's what we said about Reese Witherspoon when she collected best actress for a charismatic elevation of a borderline supporting role in Walk the Line.
There was a similar trend, of borderline statistical significance, suggesting a larger elevation in postprandial glucose in the low-gain glucagon versus placebo studies (179 ± 26 vs. 151 ± 18 mg/dl, P = 0.05).
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