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The cells were predominantly found in clusters at the border between the granular layer (GL) and the hilus (HL) (i.e., subgranular layer: SGL) of the DG (Figure S1).
HS showed also mGluR5-stained fibers of neuronal and likely glial origin, including cells with astrocytic profile near the granular layer border (Fig. 4F right, arrowheads), which were not evident in non-HS or control hilus.
Therefore, the proximal tract of the ascending dendrite unlikely forms synaptic contacts with the granule cell axons, despite its localization in the granular layer, while the distal tract is extensively bordered by PFs.
The spinous layer is succeeded by the granular layer, or stratum granulosum, with granules of keratohyalin contained in the cells.
The granular layer is idealized as Pasternak shear layer [26].
Furthermore, the granular layer as a whole gradually tilts.
In contrast, the choline uptake rate in the granular layer eventually decreased slightly.
The two yellow lines trace the surface of the granular layer and the two-layer interface.
The granular layer beneath the strip footing idealized as incompressible shear layer.
Within the granular layer, a mossy fiber generates a series of enlargements called rosettes.
Pofut1 conditional inactivation led to ultrastructural abnormalities in the granular layer and altered filaggrin processing in the epidermis, suggesting a perturbation of the granular layer differentiation.
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