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To assess significance we computed 95% confidence intervals for the difference scores (obtained by subtracting the AUC of the bootstrapped data from the AUC of the bootstrapped shuffle).
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To some extent this problem can be mitigated by producing calibration images at different exposure levels and bootstrapping data from these together.
Each estimation of the mean is based on bootstrapping data from one disc sample.
Bias-corrected CIs 25 for the ICERs were estimated from the bootstrapped data generated using the 'recycled predictions' method as described by Glick et al. 23 This technique generates a large number of bootstrapped samples (10 000 replications were used).
The cubic-spline method was then used to fit an indicator (incidence or notification) to a set of bootstrapped data, obtained by sampling from the normal error distribution with zero mean and a standard deviation of the residuals of the spline regression.
We considered that coefficients of regression were significant if fitted values on the original data were significantly larger (or smaller) than 99% of the values estimated from the bootstrapped data sets.
Data was bootstrapped 100 times and only branches that appeared in >90% of the trees formed from the 100 bootstrapped data sets were depicted.
Statistical significance of branching was verified by bootstrap analysis involving the construction and analysis of 1000 trees from bootstrapped data sets.
(A ) Distribution of response indices from bootstrapped data out of touch (left) shows that a large fraction of RS neurons are not modulated by vocalizations.
Bootstrap values for the maximum parsimony genealogy were calculated in PHYLIP from 1,000 bootstrapped data sets.
We also bootstrapped samples from a combined data set including data from biotic and abiotic traits, and calculated a mean and variance from this second set of bootstrapped data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com