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1000 bootstrap samples were created by drawing 10 subjects randomly with replacement from the original sample.
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Bootstrap samples are created by sampling with replacement from the dataset.
Each bootstrap sample was created based on random sampling by drawing with replacement and the size of each bootstrap sample is the same as in the original sample.
Each gene was re-sampled independently (using the program Seqboot from the Phylip package [ 54]) and then each bootstrap sample was created by concatenating one replicate from each gene.
One hundred bootstrap samples were generated using the SEQBOOT program [51].
First 100 bootstrap samples were generated.
Due to small sample size, 95%% bootstrap confidence intervals based on 10,000 bootstrap samples were obtained.
First, 500 bootstrap samples were generated from the original sample.
One thousand bootstrap samples were taken from the original sample with replacement, and a value of T calculated in each bootstrap sample, denoted for the ith bootstrap sample.
In the MP-EST analysis, 1000 bootstrap samples were produced using a nonparametric bootstrapping technique [ 47].
Bootstrap confidence intervals based on 1000 bootstrap samples were also estimated for all AUCs.
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