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Phylogenetic and molecular evolutionary analyses were calculated in MEGA 5.0 package by using the p-distance model, and the Neighbor-joining statistical method followed by 1000 bootstrap replications were applied [ 48].
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Since the data were highly right-skewed, non-parametric bootstrapping with 4 000 replications was applied.
Non-parametric bootstrapping with 10,000 replications was applied due to the skewed nature of both resource use and cost, and a general significance level of 0.05 was used.
For each data set, 1000 bootstrap replications were used, resulting in a bootstrap percentile confidence interval for the AMA.
Bootstrap re-sampling was conducted stratified by gastroenterologist; 1,000 bootstrap replications were performed.
The 95% confidence intervals for evolutionary parameters were calculated using bootstrap percentiles [ 51]. 2000 bootstrap replications were used.
The number of bootstrap replications was fixed at 1000.
A consensus tree following 1000 bootstrap replications are shown.
A concrete guideline will be given, how many bootstrap replications are required to fulfill a desired precision criterion.
In the bootstrap estimation 1000 bootstrap replications are used to produce the bootstrap distribution of PR.
Non-parametric bootstrapping using 10,000 replications will be applied to cost and effect data for both groups.
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