ML bootstrap proportions were inferred using 1000 replicates.
Phylogenetic relationships and bootstrap proportions were estimated using PhyML (Guindon et al. 2009) under the WAG amino acid substitution model (Whelan and Goldman 2001) with invariable and four gamma-distributed substitution rate categories.
Bootstrap technic was used to compute the confidence intervals.
Bootstrap technic was used to compute confidence interval (CI).
Bootstrapping was used to determine the proportion of dots in each quadrant of the cost-effectiveness plane.
Differences between incidence proportions were analyzed by using the 2-tailed 2-proportion z-test with a 95% CI, and nonparametric bootstrapping was used to construct a 95% CI for the relative increase in risk.
Bootstrapping was used to provide sampling standard deviations and determining confidence intervals for the proportion of annotated sequences over all taxonomic groups.
Bootstrapping was used for internal validation.
A bootstrap replication of 100 was used.
The two-sided proportion test with Yates' continuity correction was used for testing differences between proportions (except for differences between PPVs, for which bootstrapping [with 1,000 bootstrap samples] was used because the patient groups partially overlap).
