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Seq-Gen [ 80] generates 100 parametric bootstrap datasets under the RAS model using the PHYML-generated parameter estimates, and the W statistic is computed for each.
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The larger the number of wild bootstrap datasets, the more satisfactory the estimate of a statistic will be.
The locations of the LOD peaks for bootstrap datasets which exceed the threshold are ordered.
The median parameter estimates from the bootstrap datasets were comparable with the point estimates from the original dataset.
Bootstrap datasets were generated using the SEQBOOT program from the PHYLIP package ver. 3.66 [104].
Parametric bootstrap datasets were generated using the parameter estimates from the illustrative datasets as parameter values.
The 200 estimates (one estimate for each bootstrap dataset) of the calibration slope are then averaged.
One thousand bootstrap datasets were used to estimate the confidence of each tree clade.
We have adopted a similar approach to aggregate the individual biclusters identified from the bootstrap datasets.
(7) We can then obtain bootstrap estimates from the wild bootstrap datasets.
We then apply our method to each of the B bootstrap datasets.
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