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b Map showing the 95%% bootstrap confidence intervals of the horizontal tremor locations.
Likelihood-based methods including maximum likelihood estimates, asymptotic and bootstrap confidence intervals of parameters of interest are derived.
Table 8 lists the results of the bootstrap procedure, presented as mean and 95% bootstrap confidence intervals of the parameter estimates and random effects of the final model.
For completeness, we also calculated the 95% simple bootstrap confidence intervals of the expected time (BCa method) [ 26, 27] based on 5000 bootstrap samples, for the truncation-based approach.
Therefore, we evaluated the bootstrap as a technique for statistically testing the RV and, furthermore, used simulations to investigate factors that may affect the bootstrap confidence intervals of the RV under different conditions.
This is consistent with population genetics theory that predicts neutral variants linked to deleterious alleles should be found at lower frequencies [ 41]. 95% bootstrap confidence intervals of mean allele frequency ranged from 0.3802 to 0.4076.
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* Means that is outside of the 95% bootstrap confidence interval of the genome mean.
The bioavailability estimate for levodopa from LCIG relative to LC-oral was 97%95%5% bootstrap confidence interval of 95%to98%8%).
We initially suspected that the sample size would play a prominent role in determining the bootstrap confidence interval of the RV.
Moreover, we can see that the 95% point-wise bootstrap confidence interval of the current cumulative incidence curve is wider than the corresponding confidence interval of the common cumulative incidence curve as time increases.
Levodopa steady-state volume of distribution (Vc + Vp) (131 l, 95% bootstrap confidence interval of 63.6 to 461 l) is at the upper end of the reported range of 15.4 to 124 l across different analysis methodologies 23.
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