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Resampling of differential travel times was conducted 2000 times, and the 95%% bootstrap confidence interval was used as the estimation error.
We found GAM's to perform as well as nonlinear models with respect to fit and validation statistics; however, when applied to the population of predictor data the bootstrap confidence interval was less efficient than the null model.
The corresponding 95% percentile bootstrap confidence interval was calculated for each gene.
Then the CCj was calculated as the average CC for the 2000 re-samples and the 95% bootstrap confidence interval was estimated.
When the 95% bootstrap confidence interval was not confined to a single fraction, the definition of the peak fraction was widened from only one to two (or more) adjacent fractions and a search for the maximum was initiated again.
When the 95% bootstrap confidence interval was not confined to a single fraction, the definition of the peak fraction was widened from only one to two (or more) adjacent fractions and the search for the maximum was started again.
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In the next section, a possible measure of spread for 3-D rotations is introduced and the steps for obtaining a bootstrap confidence interval are outlined.
We did 1000 bootstraps and the 95% bootstrap confidence interval is (0.404, 0.446).
An additional bootstrap confidence interval is listed if this option was chosen in the job submission form.
Moreover, with this method, only a bootstrap confidence interval is available though the bootstrap coverage probability is not always acceptable for optimal thresholds [ 6].
The sample size for the bootstrap confidence intervals was 999.
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